Changes in Staphylococcus aureus susceptibility across Latin America between 2004 and 2010

Garza González, Elvira y Dowzicky, Michael Joseph (2013) Changes in Staphylococcus aureus susceptibility across Latin America between 2004 and 2010. The Brazilian Journal of Infectious Diseases, 17 (1). pp. 13-19. ISSN 14138670

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Resumen

The Tigecycline Evaluation and Surveillance Trial is a global surveillance study monitoring the efficacy of tigecycline and comparators against clinically important pathogens. Between 2004 and 2010, 3126 isolates of Staphylococcus aureus were collected from 66 centers in 13 countries in Latin America; of these, 1467 (46.9%) were resistant to methicillin. The main contributors of S. aureus isolates were Mexico (n = 846), Argentina (n = 740), and Colombia (n = 445). The methicillin-resistant S. aureus rate was greater than 50% in five countries, the highest reported in Puerto Rico (73.9%). Methicillin-resistant S. aureus rates across Latin America ranged from 40.1% to 50.6% over the study period. All S. aureus isolates were susceptible to linezolid and vancomycin, while 100% of methicillin-susceptible S. aureus isolates and 99.8% of methicillin-resistant S. aureus isolates were susceptible to tigecycline. Both methicillin-susceptible S. aureus and methicillin-resistant S. aureus were highly susceptible to minocycline (99.2% and 97.0%, respectively). Latin American methicillinsusceptible S. aureus were highly susceptible to levofloxacin (94.6%) while only 16.2% of methicillin-resistant S. aureus were levofloxacin-susceptible. This study shows that linezolid, vancomycin, and tigecycline are all highly active against S. aureus from Latin America, regardless of methicillin resistance.

Tipo de elemento: Article
Palabras claves no controlados: Tigecycline, Antimicrobial surveillance, Latin America, Staphylococcus aureus
Divisiones: Medicina
Usuario depositante: Lic. Josimar Pulido
Creadores:
CreadorEmailORCID
Garza González, ElviraNO ESPECIFICADONO ESPECIFICADO
Dowzicky, Michael JosephNO ESPECIFICADONO ESPECIFICADO
Fecha del depósito: 17 Mayo 2019 14:58
Última modificación: 17 Mayo 2019 14:58
URI: http://eprints.uanl.mx/id/eprint/14906

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