Identification of Differentially Expressed Genes Associated with Prognosis of B Acute Lymphoblastic Leukemia

Garza Veloz, Idalia y Martinez Fierro, Margarita L. y Jaime Pérez, José Carlos y Carrillo Sanchez, Karol y Ramos Del Hoyo, Maria Guadalupe y Lugo Trampe, Ángel y Rojas Martínez, Augusto y Gutiérrez Aguirre, César Homero y González Llano, Óscar y Salazar Riojas, Rosario y Hidalgo Miranda, Alfredo y Gómez Almaguer, David y Ortiz López, Rocío (2015) Identification of Differentially Expressed Genes Associated with Prognosis of B Acute Lymphoblastic Leukemia. Disease Markers, 2015. pp. 1-11. ISSN 0278-0240

[img]
Vista previa
Texto
134.pdf - Versión Publicada
Available under License Creative Commons Attribution Non-commercial No Derivatives.

Download (1MB) | Vista previa
URL o página oficial: http://doi.org/10.1155/2015/828145

Resumen

Acute lymphoblastic leukemia type B (B-ALL) is a neoplastic disorder with high mortality rates. The aim of this study was to validate the expression profile of 45 genes associated with signaling pathways involved in leukemia and to evaluate their association with the prognosis of B-ALL. Methods. 219 samples of peripheral blood mononuclear cells obtained from 73 B-ALL patients were studied at diagnosis, four, and eight weeks after starting treatment. Gene expression was analyzed by quantitative realtime polymerase chain reaction. Results. Normalized delta Cq values of 23 genes showed differences between B-ALL and controls at diagnosis time (

Tipo de elemento: Article
Divisiones: Medicina
Usuario depositante: Editor Repositorio
Creadores:
CreadorEmailORCID
Garza Veloz, IdaliaNO ESPECIFICADONO ESPECIFICADO
Martinez Fierro, Margarita L.NO ESPECIFICADONO ESPECIFICADO
Jaime Pérez, José CarlosNO ESPECIFICADONO ESPECIFICADO
Carrillo Sanchez, KarolNO ESPECIFICADONO ESPECIFICADO
Ramos Del Hoyo, Maria GuadalupeNO ESPECIFICADONO ESPECIFICADO
Lugo Trampe, ÁngelNO ESPECIFICADONO ESPECIFICADO
Rojas Martínez, AugustoNO ESPECIFICADONO ESPECIFICADO
Gutiérrez Aguirre, César HomeroNO ESPECIFICADONO ESPECIFICADO
González Llano, ÓscarNO ESPECIFICADONO ESPECIFICADO
Salazar Riojas, RosarioNO ESPECIFICADONO ESPECIFICADO
Hidalgo Miranda, AlfredoNO ESPECIFICADONO ESPECIFICADO
Gómez Almaguer, DavidNO ESPECIFICADONO ESPECIFICADO
Ortiz López, RocíoNO ESPECIFICADONO ESPECIFICADO
Fecha del depósito: 14 Mayo 2019 21:42
Última modificación: 14 Mayo 2019 21:42
URI: http://eprints.uanl.mx/id/eprint/14975

Actions (login required)

Ver elemento Ver elemento

Downloads

Downloads per month over past year