Understanding the colon cancer stem cells and perspectives on treatment

Garza Treviño, Elsa Nancy y Said Fernández, Salvador y Martínez Rodríguez, Herminia Guadalupe (2015) Understanding the colon cancer stem cells and perspectives on treatment. Cancer cell international, 15 (1). p. 2. ISSN 1475-2867

Vista previa

Texto
182.pdf - Versión Publicada
Available under License Creative Commons Attribution Non-commercial No Derivatives.
Download (669kB) | Vista previa

URL o página oficial: http://doi.org/10.1186/s12935-015-0163-7

Resumen

An area of research that has been recently gaining attention is the relationship between cancer stem cell (CSC) biology and chemo-resistance in colon cancer patients. It is well recognized that tumor initiation, growth, invasion and metastasis are promoted by CSCs. An important reason for the widespread interest in the CSC model is that it can comprehensibly explain essential and poorly understood clinical events, such as therapy resistance, minimal residual disease, and tumor recurrence. This review discusses the recent advances in colon cancer stem cell research, the genes responsible for CSC chemoresistance, and new therapies against CSCs.

Tipo de elemento:

Article

Palabras claves no controlados:

Cancer stem cells, Chemoresistance, Colon cance

Divisiones:

Medicina

Usuario depositante:

Editor Repositorio

Creadores:

Creador	Email	ORCID
Garza Treviño, Elsa Nancy	elsa.garzatr@uanl.edu.mx	orcid.org/0000-0002-1042-4603
Said Fernández, Salvador	NO ESPECIFICADO	NO ESPECIFICADO
Martínez Rodríguez, Herminia Guadalupe	NO ESPECIFICADO	NO ESPECIFICADO