Diabetic myonecrosis in a patient with hepatic cirrhosis: a case report and review of the literature

Mancillas Adame, Leonardo G. y González González, José Gerardo y Jáquez Quintana, Joel Omar y Cardoza Torres, Myrna A. y García, Alberto de la Fuente (2009) Diabetic myonecrosis in a patient with hepatic cirrhosis: a case report and review of the literature. Journal of medical case reports, 3 (1). pp. 1-5. ISSN 1752-1947

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URL o página oficial: http://doi.org/10.1186/1752-1947-3-9305

Resumen

Introduction: Diabetic myonecrosis was first reported by Angervall and Stener in 1965. In its classical clinical expression, it affects type 1 diabetes mellitus patients with long-standing poor metabolic control and advanced chronic microvascular complications. A sudden-onset of severe pain in the region of the involved muscle, usually the quadriceps, is the typical clinical manifestation. Magnetic resonance imaging (MRI) confirms the clinical diagnosis; in some cases of diagnostic uncertainty, a muscle biopsy may be required. Case Presentation: We present the case of a 38 year-old Hispanic male from Mexico, with alcohol-induced hepatic cirrhosis (Child-Pugh C/MELD 45) and type 2 diabetes mellitus admitted to the emergency room due to hepatic encephalopathy with intense pain and an increase in volume of the left thigh. MRI showed edema and inflammatory changes of the quadriceps muscle with a hyperintense signal on T2-weighted images; in addition, there was a subacute hematoma. Conclusion: To the best of our knowledge, this is the first case of diabetic myonecrosis associated with and complicated by advanced hepatic cirrhosis reported in the literature.

Tipo de elemento:

Article

Divisiones:

Medicina

Usuario depositante:

Lic. Josimar Pulido

Creadores:

Creador	Email	ORCID
Mancillas Adame, Leonardo G.	NO ESPECIFICADO	NO ESPECIFICADO
González González, José Gerardo	gerardo.gonzalezgzz@uanl.edu.mx	orcid.org/0000-0002-6609-9483
Jáquez Quintana, Joel Omar	jomjaqui@hotmail.com	NO ESPECIFICADO
Cardoza Torres, Myrna A.	NO ESPECIFICADO	NO ESPECIFICADO
García, Alberto de la Fuente	NO ESPECIFICADO	NO ESPECIFICADO