Clinical features and outcome of mucormycosis

Camara Lemarroy, Carlos Rodrigo y González Moreno, Emmanuel Irineo y Rodríguez Gutiérrez, René y Rendón Ramírez, Erick Joel y Ayala Cortés, Ana Sofía y Fraga Hernández, Martha Lizeth y García Labastida, Laura y Galarza Delgado, Dionicio Ángel (2014) Clinical features and outcome of mucormycosis. Interdisciplinary Perspectives on Infectious Diseases, 2014. pp. 1-5. ISSN 1687-708X

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URL o página oficial: http://doi.org/10.1155/2014/562610

Resumen

Mucormycosis (MCM) is a life-threatening infection that carries high mortality rates despite recent advances in its diagnosis and treatment. The objective was to report 14 cases of mucormycosis infection and review the relevant literature. We retrospectively analyzed the demographic and clinical data of 14 consecutive patients that presented with MCM in a tertiary-care teaching hospital in northern Mexico. The mean age of the patients was 39.9 (range 5–65). Nine of the patients were male. Ten patients had diabetes mellitus as the underlying disease, and 6 patients had a hematological malignancy (acute leukemia). Of the diabetic patients, 3 had chronic renal failure and 4 presented with diabetic ketoacidosis. All patients had rhinocerebral involvement. In-hospital mortality was 50%. All patients received medical therapy with polyene antifungals and 11 patients underwent surgical therapy. Survivors were significantly younger and less likely to have diabetes than nonsurvivors, and had higher levels of serum albumin on admission. The clinical outcome of patients with MCM is poor. Uncontrolled diabetes and age are negative prognostic factors.

Tipo de elemento: Article
Materias: Q Ciencia > QR Microbiología
R Medicina > RC Medicina Interna, Psiquiatría, Neurología
Divisiones: Medicina
Usuario depositante: Lic. Jesús E. Alvarado
Creadores:
CreadorEmailORCID
Camara Lemarroy, Carlos RodrigoNO ESPECIFICADONO ESPECIFICADO
González Moreno, Emmanuel IrineoNO ESPECIFICADONO ESPECIFICADO
Rodríguez Gutiérrez, RenéNO ESPECIFICADONO ESPECIFICADO
Rendón Ramírez, Erick JoelNO ESPECIFICADONO ESPECIFICADO
Ayala Cortés, Ana SofíaNO ESPECIFICADONO ESPECIFICADO
Fraga Hernández, Martha LizethNO ESPECIFICADONO ESPECIFICADO
García Labastida, LauraNO ESPECIFICADONO ESPECIFICADO
Galarza Delgado, Dionicio ÁngelNO ESPECIFICADONO ESPECIFICADO
Fecha del depósito: 27 Mar 2019 21:58
Última modificación: 27 Mar 2019 21:58
URI: http://eprints.uanl.mx/id/eprint/15221

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