Angioimmunoblastic T-Cell lymphoma: a diagnostic challenge

Ocampo Garza, Jorge y Herz Ruelas, Maira Elizabeth y González Lopez, Elias Eugenio y Mendoza Oviedo, Eric Eduardo y Garza Chapa, Juana Irma y Ocampo Garza, Sonia Sofía y Vázquez Herrera, Norma Elizabeth y Miranda Maldonado, Ivett C. y Ocampo Candiani, Jorge (2014) Angioimmunoblastic T-Cell lymphoma: a diagnostic challenge. Case Reports in Dermatology, 6 (3). pp. 291-295. ISSN 1662-6567

[img]
Vista previa
Texto
337.pdf - Versión Publicada
Available under License Creative Commons Attribution Non-commercial No Derivatives.

Download (960kB) | Vista previa
URL o página oficial: http://doi.org/10.1159/000370302

Resumen

Angioimmunoblastic T-cell lymphoma (AITL) accounts for 15–20% of all peripheral T-cell lymphomas. It is a rare subtype of CD4 T-cell peripheral lymphoma that affects aged individuals, causing B symptoms, generalized lymphadenopathy and hepatosplenomegaly. Its pathogenesis is still unclear, but in some cases it has been associated with infection, allergic reaction or drug exposure. The majority of patients are diagnosed in an advanced stage and anthracycline based regimen is considered the first-line therapy. Skin involvement is not well characterized, occurring in up to 50% of patients and presenting as nonspecific rash, macules, papules, petechiae, purpura, nodules and urticaria. We present the illustrative case of a 55-year-old woman with an AITL who presented prominent skin findings, arthritis, lymphadenopathy and hypereosinophilia. Skin biopsy reported a T-cell lymphoma and the diagnosis of AITL was confirmed by an axillary lymph node biopsy, which was also positive for EpsteinBarr virus. Chemotherapy with CHOP-21 and thalidomide was given, accomplishing complete remission after six cycles.

Tipo de elemento: Article
Palabras claves no controlados: Lymphoma; Angioimmunoblastic T-cell lymphoma; Cutaneous involvement; Epstein-Barr virus
Materias: R Medicina > RL Dermatología
Divisiones: Medicina
Usuario depositante: Editor Repositorio
Creadores:
CreadorEmailORCID
Ocampo Garza, JorgeNO ESPECIFICADONO ESPECIFICADO
Herz Ruelas, Maira ElizabethNO ESPECIFICADONO ESPECIFICADO
González Lopez, Elias EugenioNO ESPECIFICADONO ESPECIFICADO
Mendoza Oviedo, Eric EduardoNO ESPECIFICADONO ESPECIFICADO
Garza Chapa, Juana IrmaNO ESPECIFICADONO ESPECIFICADO
Ocampo Garza, Sonia SofíaNO ESPECIFICADONO ESPECIFICADO
Vázquez Herrera, Norma ElizabethNO ESPECIFICADONO ESPECIFICADO
Miranda Maldonado, Ivett C.NO ESPECIFICADONO ESPECIFICADO
Ocampo Candiani, JorgeNO ESPECIFICADONO ESPECIFICADO
Fecha del depósito: 12 Mar 2019 22:11
Última modificación: 12 Mar 2019 22:11
URI: http://eprints.uanl.mx/id/eprint/15235

Actions (login required)

Ver elemento Ver elemento

Downloads

Downloads per month over past year