Clostridioides difficile-associated diarrhea in surgical service patients in Mexico

Morfín Otero, R. y Petersen Morfín, S. y Aguirre Diaz, Sara Alejandra y Pérez Gómez, H.R. y Garza González, E. y González Díaz, E. y Esparza Ahumada, S. y Velarde Ruiz Velasco, J.A. y León Garnica, G. y Escobedo Sánchez, R. y Rodríguez Noriega, E. (2020) Clostridioides difficile-associated diarrhea in surgical service patients in Mexico. Revista de Gastroenterología de México (English Edition), 85 (3). pp. 227-234. ISSN 2255-534X

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Resumen

Introduction: Clostridium difficile is the first cause of healthcare-associated diarrhea in developed countries. In recent years the incidence of C. difficile infection (CDI) has increased worldwide. There is not much information on the topic in Mexico, and little is known about the risk factors for the infection in patients that are hospitalized in surgical services. Materials and methods: A case-control study was conducted that compared the epidemiologic findings and risk factors between surgical patients with PCR-confirmed CDI, surgical patients with diarrhea and a negative PCR test, and surgical patients with no diarrhea. The statistical analysis was carried out using the SPSS version 22.0 program. Results: The majority of the surgical patients with CDI belonged to the areas of neurosurgery, cardiac surgery, orthopedics, and general surgery. A total of 53% of the CDI cases were associated with the hypervirulent CD NAP1/027 strain. The presence of mucus in stools (OR: 1.5, p = 0.001), fever (OR: 1.4, p = 0.011), leukocytes in stools (OR: 3.2, p < 0.001), hospitalization within the past twelve weeks (OR: 2.0, p < 0.001), antibiotic use (OR: 1.3, p = 0.023), and ceftriaxone use (OR: 1.4, p = 0.01) were independent risk factors for the development of CDI.

Tipo de elemento: Article
Palabras claves no controlados: Diarrea, Clostridium difficile, Infecciones, Cirugía.
Materias: R Medicina > RC Medicina Interna, Psiquiatría, Neurología
Divisiones: Medicina
Usuario depositante: Editor Repositorio
Creadores:
CreadorEmailORCID
Morfín Otero, R.NO ESPECIFICADONO ESPECIFICADO
Petersen Morfín, S.NO ESPECIFICADONO ESPECIFICADO
Aguirre Diaz, Sara AlejandraNO ESPECIFICADONO ESPECIFICADO
Pérez Gómez, H.R.NO ESPECIFICADONO ESPECIFICADO
Garza González, E.NO ESPECIFICADONO ESPECIFICADO
González Díaz, E.NO ESPECIFICADONO ESPECIFICADO
Esparza Ahumada, S.NO ESPECIFICADONO ESPECIFICADO
Velarde Ruiz Velasco, J.A.NO ESPECIFICADONO ESPECIFICADO
León Garnica, G.NO ESPECIFICADONO ESPECIFICADO
Escobedo Sánchez, R.NO ESPECIFICADONO ESPECIFICADO
Rodríguez Noriega, E.NO ESPECIFICADONO ESPECIFICADO
Fecha del depósito: 13 Oct 2020 14:19
Última modificación: 28 Oct 2020 02:52
URI: http://eprints.uanl.mx/id/eprint/20049

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