Male Sexual Health and Reproduction in Cutaneous Immune-Mediated Diseases: A Systematic Review

Perez Garcia, Luis F. y Dolhain, Radboud y te Winkel, Bernke y Carrizales, Juan P. y Bramer, Wichor M. y Vorstenbosch, Saskia y van Puijenbroek, Eugene y Hazes, Mieke y van Doorn, Martijn B.A. (2020) Male Sexual Health and Reproduction in Cutaneous Immune-Mediated Diseases: A Systematic Review. Sexual Medicine Reviews. ISSN 2050-0521 (Por publicarse)

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Introduction: Information about the possible effects of cutaneous immune-mediated diseases (cIMDs) on male sexual function and reproduction is scarce. Factors known to impair sexual health and reproduction, such as inflammation, medication use, and hypogonadism, can be present in a significant proportion of male patients with cIMD. Objectives: To systematically review the literature for the influence of paternal cIMD on many aspects of male sexual and reproductive health, such as sexual function, reproductive hormones, fertility, and pregnancy and offspring outcomes. Methods: A systematic literature search was performed. The searches combined keywords regarding male sexual function and fertility, pregnancy outcomes, and offspring's health with a list of cIMDs. Results: The majority of the identified studies included patients with psoriasis (22 of 27), and sexual function was the most common outcome of interest (20 of 27). For patients diagnosed with psoriasis, the prevalence of male sexual dysfunction reported in these studies ranged from 34 to 81%. Hypogonadism in patients with psoriasis was reported in 2 of 3 studies. Sperm analysis abnormalities in patients with psoriasis were reported in 3 of 4 studies. No information about the effect of paternal disease on pregnancy and offspring outcomes was identified. Conclusions: Disease activity in psoriasis might play an important role in the development of sexual dysfunction, hypogonadism, and abnormal sperm quality. For the other cIMD included in this review, there is insufficient information regarding male sexual and reproductive health to draw firm conclusions. More research is needed to understand the association between cIMD and impaired male sexual and reproductive health.

Tipo de elemento: Article
Palabras claves no controlados: Immune-Mediated Cutaneous Diseases, Sexual and Reproductive Health, Sexual Dysfunction, Male, Sexual Function, Inflammation
Materias: R Medicina > RC Medicina Interna, Psiquiatría, Neurología
Divisiones: Medicina
Usuario depositante: Editor Repositorio
Creadores:
CreadorEmailORCID
Perez Garcia, Luis F.NO ESPECIFICADONO ESPECIFICADO
Dolhain, RadboudNO ESPECIFICADONO ESPECIFICADO
te Winkel, BernkeNO ESPECIFICADONO ESPECIFICADO
Carrizales, Juan P.NO ESPECIFICADONO ESPECIFICADO
Bramer, Wichor M.NO ESPECIFICADONO ESPECIFICADO
Vorstenbosch, SaskiaNO ESPECIFICADONO ESPECIFICADO
van Puijenbroek, EugeneNO ESPECIFICADONO ESPECIFICADO
Hazes, MiekeNO ESPECIFICADONO ESPECIFICADO
van Doorn, Martijn B.A.NO ESPECIFICADONO ESPECIFICADO
Fecha del depósito: 15 Oct 2020 12:55
Última modificación: 15 Oct 2020 12:55
URI: http://eprints.uanl.mx/id/eprint/20102

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