Wordwide patterns of genetic differentiation imply multiple ‘domestications’of Aedes aegypti, a major vector of human diseases

Brown, Julia E. y McBride, Carolyn S. y Johnson, Petrina y Ritchie, Scott y Paupy, Christophe y Bossin, Herve y Lutomiah, Joel y Fernández Salas, Ildefonso y Ponlawat, A. y Cornel, A. J. y Black, William C. y Gorrochótegui Escalante, Norma y Urdaneta Márquez, L. y Sylla, M. y Slotman, M. y Murray, Kristy O. y Walker, C. y Powell, Jeffrey R. (2011) Wordwide patterns of genetic differentiation imply multiple ‘domestications’of Aedes aegypti, a major vector of human diseases. Proceedings of the Royal Society. B, Biological sciences, 278. pp. 2446-2454. ISSN 1471-2954

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URL o página oficial: doi:10.1098/rspb.2010.2469

Resumen

Understanding the processes by which species colonize and adapt to human habitats is particularly important in the case of disease-vectoring arthropods. The mosquito species Aedes aegypti, a major vector of dengue and yellow fever viruses, probably originated as a wild, zoophilic species in sub-Saharan Africa, where some populations still breed in tree holes in forested habitats. Many populations of the species, however, have evolved to thrive in human habitats and to bite humans. This includes some populations within Africa as well as almost all those outside Africa. It is not clear whether all domestic populations are genetically related and represent a single ‘domestication’ event, or whether association with human habitats has developed multiple times independently within the species. To test the hypotheses above, we screened 24 worldwide population samples of Ae. aegypti at 12 polymorphic microsatellite loci. We identified two distinct genetic clusters: one included all domestic populations outside of Africa and the other included both domestic and forest populations within Africa. This suggests that human association in Africa occurred independently from that in domestic populations across the rest of the world. Additionally, measures of genetic diversity support Ae. aegypti in Africa as the ancestral form of the species. Individuals from domestic populations outside Africa can reliably be assigned back to their population of origin, which will help determine the origins of new introductions of Ae. aegypti.

Tipo de elemento: Article
Materias: ?? QH301 ??
?? QH426 ??
Divisiones: Ciencias Biológicas
Usuario depositante: Admin Eprints
Creadores:
CreadorEmailORCID
Brown, Julia E.NO ESPECIFICADONO ESPECIFICADO
McBride, Carolyn S.NO ESPECIFICADONO ESPECIFICADO
Johnson, PetrinaNO ESPECIFICADONO ESPECIFICADO
Ritchie, ScottNO ESPECIFICADONO ESPECIFICADO
Paupy, ChristopheNO ESPECIFICADONO ESPECIFICADO
Bossin, HerveNO ESPECIFICADONO ESPECIFICADO
Lutomiah, JoelNO ESPECIFICADONO ESPECIFICADO
Fernández Salas, IldefonsoNO ESPECIFICADONO ESPECIFICADO
Ponlawat, A.NO ESPECIFICADONO ESPECIFICADO
Cornel, A. J.NO ESPECIFICADONO ESPECIFICADO
Black, William C.NO ESPECIFICADONO ESPECIFICADO
Gorrochótegui Escalante, NormaNO ESPECIFICADONO ESPECIFICADO
Urdaneta Márquez, L.NO ESPECIFICADONO ESPECIFICADO
Sylla, M.NO ESPECIFICADONO ESPECIFICADO
Slotman, M.NO ESPECIFICADONO ESPECIFICADO
Murray, Kristy O.NO ESPECIFICADONO ESPECIFICADO
Walker, C.NO ESPECIFICADONO ESPECIFICADO
Powell, Jeffrey R.NO ESPECIFICADONO ESPECIFICADO
Fecha del depósito: 28 Ene 2011 19:38
Última modificación: 24 Nov 2014 20:49
URI: http://eprints.uanl.mx/id/eprint/2322

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