Candidate gene polymorphisms and risk of psoriasis: A pilot study

Villarreal Martínez, Alejandra y Gallardo Blanco, Hugo L. y Cerda Flores, Ricardo Martín y Torres Muñoz, Iris Carmen y Gómez Flores, Minerva y Salas Alanís, Julio César y Ocampo Candiani, Jorge y Martíez Garza, Laura (2016) Candidate gene polymorphisms and risk of psoriasis: A pilot study. Experimental and Therapeutic Medicine, 11 (4). pp. 1217-1222. ISSN 1792-0981, 1792-1015

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Resumen

Psoriasis is a complex genetic disease, which has previously been associated with numerous single nucleotide polymorphisms (SNPs) that are implicated in various processes, including skin barrier functions and in the regulation of inflammatory and immune responses. The present study aimed to investigate the genotypic and allelic frequencies of 32 SNPs at 24 genetic loci, and their association with psoriasis in a Mexican population. These SNPs, which were associated with psoriasis in previous studies, included the following genes: Major histocompatibility complex class I-C (HLA‑C), interleukin (IL)-12B, IL‑23R, IL‑23A, IL‑28RA, tumor necrosis factor (TNF)-α, ring finger protein‑114 (RNF114), cyclin-dependent kinase 5 regulatory subunit-associated protein 1-like 1, late cornified envelope 3B/3C, signal transducer and activator of transcription

Tipo de elemento:	Article
Palabras claves no controlados:	Gene association, Genetic risk, Polymorphisms, Psoriasis genes
Materias:	CONACYT > Biología y Química CONACYT > Medicina y Ciencias de la Salud
Divisiones:	Medicina
Usuario depositante:	Dr.C. Hugo Gallardo Blanco
Creadores:	Creador Email ORCID Villarreal Martínez, Alejandra NO ESPECIFICADO NO ESPECIFICADO Gallardo Blanco, Hugo L. hugo.gallardobl@uanl.edu.mx orcid.org/0000-0002-7816-4967 Cerda Flores, Ricardo Martín NO ESPECIFICADO NO ESPECIFICADO Torres Muñoz, Iris Carmen NO ESPECIFICADO NO ESPECIFICADO Gómez Flores, Minerva NO ESPECIFICADO NO ESPECIFICADO Salas Alanís, Julio César NO ESPECIFICADO NO ESPECIFICADO Ocampo Candiani, Jorge jocampo2000@yahoo.com.mx orcid.org/0000-0002-0213-0031 Martíez Garza, Laura NO ESPECIFICADO NO ESPECIFICADO
Fecha del depósito:	04 Sep 2026 16:44
Última modificación:	04 Sep 2026 16:44
URI:	http://eprints.uanl.mx/id/eprint/31437

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