The impact of exercise intensity on the release of cardiac biomarkers in marathon runners

Legaz Arrese, Alejandro y George, Keith y Carranza García, Luis Enrique y Munguía Izquierdo, Diego y Moros García, Teresa y Serrano Ostáriz, Enrique (2011) The impact of exercise intensity on the release of cardiac biomarkers in marathon runners. European journal of applied physiology, 111 (12). pp. 2961-2967. ISSN 1439-6319

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Resumen

We sought to determine the influence of exercise intensity on the release of cardiac troponin I (cTnI) and N-terminal pro-brain natriuretic peptide (NT-proBNP) in amateur marathon runners. Fourteen runners completed three exercise trials of the same duration but at exercise intensities corresponding to: (a) a competitive marathon [mean ± SD: heart rate 159 ± 7 beat min-1 , finish time 202 ± 14 min]; (b) 95% of individual anaerobic threshold [heart rate 144 ± 6 beat min-1 ] and; (c) 85% of individual anaerobic threshold [heart rate 129 ± 5 beat min-1 ]. cTnI and NT-proBNP were assayed from blood samples collected before, 30 min and 3 h post-exercise for each trial. cTnI and NT-proBNP were not different at baseline before each trial. After exercise at 85% of individual anaerobic threshold cTnI was not significantly elevated. Conversely, cTnI was elevated after exercise at 95% of individual anaerobic threshold (0.016 lg L-1) and to an even greater extent after exercise at competition intensity (0.054 lg L-1 ). Peak post-exercise values of NT-proBNP were elevated to a similar extent after all exercise trials (P\0.05). The upper reference limit for cTnI (0.04 lg L-1 ) was exceeded in six subjects at competition intensity. No data for NT-proBNP surpassed its upper reference limit. Peak post-exercise values for cTnI and NTproBNP were correlated with their respective baseline values. These data suggest exercise intensity influences the release of cTnI, but not NT-proBNP, and that competitive marathon running intensity is required for cTnI to be elevated over its upper reference limit

Tipo de elemento:

Article

Palabras claves no controlados:

cTnI, NT-proBNP, Cardiac damage, Amateur runners

Materias:

G Geografía, Antropología, Recreación > GV Deportes y Recreación

Divisiones:

Organización Deportiva

Usuario depositante:

Dr Luis Enrique Carranza García

Creadores:

Creador	Email	ORCID
Legaz Arrese, Alejandro	NO ESPECIFICADO	orcid.org/0000-0003-2644-9386
George, Keith	NO ESPECIFICADO	NO ESPECIFICADO
Carranza García, Luis Enrique	luis.carranzagr@uanl.edu.mx	orcid.org/0000-0002-8876-2434
Munguía Izquierdo, Diego	NO ESPECIFICADO	orcid.org/0000-0001-7817-747X
Moros García, Teresa	NO ESPECIFICADO	NO ESPECIFICADO
Serrano Ostáriz, Enrique	NO ESPECIFICADO	NO ESPECIFICADO