Erythema Nodosum: A Practical Approach and Diagnostic Algorithm

Pérez Garza, Daniela Michelle y Chávez Álvarez, Sonia y Ocampo Candiani, Jorge y Gómez Flores, Minerva (2021) Erythema Nodosum: A Practical Approach and Diagnostic Algorithm. American Journal of Clinical Dermatology, 22 (3). pp. 367-378. ISSN 1175-0561

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URL o página oficial: http://doi.org/10.1007/s40257-021-00592-w

Resumen

Erythema nodosum is the most common form of panniculitis and is characterized by tender erythematous nodules mainly in the lower limbs on the pretibial area. The exact cause of erythema nodosum is unknown, although it appears to be a hypersensitivity response to a variety of antigenic stimuli. Although the etiology is mostly idiopathic, ruling out an underlying disease is imperative before diagnosing primary erythema nodosum. Erythema nodosum can be the first sign of a systemic disease that is triggered by a large group of processes, such as infections, inflammatory diseases, neoplasia, and/or drugs. The most common identifiable causes are streptococcal infections, primary tuberculosis, sarcoidosis, Behçet disease, inflammatory bowel disease, drugs, and pregnancy. We propose a diagnostic algorithm to optimize the initial work-up, hence initiating prompt and accurate management of the underlying disease. The algorithm includes an initial assessment of core symptoms, diagnostic work-up, differential diagnosis, and recommended therapies. Several treatment options for the erythema nodosum lesions have been previously reported; nevertheless, these options treat the symptoms, but not the triggering cause. Making an accurate diagnosis will allow the physician to treat the underlying cause and determine an optimal therapeutic strategy.

Tipo de elemento:

Article

Materias:

R Medicina > RL Dermatología

Usuario depositante:

Editor Repositorio

Creadores:

Creador	Email	ORCID
Pérez Garza, Daniela Michelle	daniela.perezgarza@gmail.com	orcid.org/0000-0002-7059-5199
Chávez Álvarez, Sonia	NO ESPECIFICADO	NO ESPECIFICADO
Ocampo Candiani, Jorge	jocampo2000@yahoo.com.mx	orcid.org/0000-0002-0213-0031
Gómez Flores, Minerva	NO ESPECIFICADO	NO ESPECIFICADO