Combined therapy in diabetic macular edema

González Cortés, Jesús Hernán y Toledo Negrete, Juan José y Butrón Valdez, K. y Zapata Elizondo, V. y Martínez Gamero, Bertha Olivia y Treviño Cavazos, Ezequiel Enrique y Guerra Leal, Jesús Dante y Mohamed Hamsho, Jesús (2015) Combined therapy in diabetic macular edema. Medicina universitaria, 17 (68). pp. 153-157. ISSN 1665-5796

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Resumen

Purpose: To determine the effectiveness of three different combinations for the ‘‘loading phase’’ in the treatment of diabetic macular edema (DME), using bevacizumab (BVZ), triamcinolone (TCL) and subthreshold macular photocoagulation (SMPC). Methods: Experimental, longitudinal, prospective, comparative and blind. Patients were randomly assigned to three treatment branches: Group 1: BVZ + SMPC (12 eyes), Group 2: SMPC + BVZ + TCL (7 eyes), Group 3: BVZ + TCL (11 eyes). Treatment with BVZ and TCL was given every 4 weeks for 3 months, SMPC was applied once at the beginning of treatment. Initial and final measurements of best corrected visual acuity (BCVA), central macular thickness (CMT) and intraocular pressure (IOP) were tested. Results: The improvement in BCVA and the reduction in CMT was statistically superior in group of BVZ + SMPCwhen compared to the other groups. There were no differences in IOP. Conclusions: Combined therapies in the ‘‘loading phase’’are a good option when treating DME. Although the group with BVZ + SMPC obtained the best results, further studies with longer followup and a higher number of participants to establish this combined therapy as the first treatment option are required.

Tipo de elemento: Article
Palabras claves no controlados: Diabetic macular edema; Bevacizumab; Laser; Subthreshold laser; Triamcinolone
Materias: R Medicina > RM Terapéutica, Farmacología
Divisiones: Medicina
Usuario depositante: Editor Repositorio
Creadores:
CreadorEmailORCID
González Cortés, Jesús Hernándrjesusgzz@gmail.comNO ESPECIFICADO
Toledo Negrete, Juan JoséNO ESPECIFICADONO ESPECIFICADO
Butrón Valdez, K.NO ESPECIFICADONO ESPECIFICADO
Zapata Elizondo, V.NO ESPECIFICADONO ESPECIFICADO
Martínez Gamero, Bertha OliviaNO ESPECIFICADONO ESPECIFICADO
Treviño Cavazos, Ezequiel EnriqueNO ESPECIFICADONO ESPECIFICADO
Guerra Leal, Jesús DanteNO ESPECIFICADONO ESPECIFICADO
Mohamed Hamsho, JesúsNO ESPECIFICADONO ESPECIFICADO
Fecha del depósito: 08 Nov 2016 21:17
Última modificación: 04 Ago 2021 16:28
URI: http://eprints.uanl.mx/id/eprint/11641

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