Nasal eosinophilic angiocentric fibrosis with IgG4-positive plasma cell infiltration

Sáenz Ibarra, Bárbara y Ceceñas Falcón, Luis Ángel y Cárdenas de la Garza, J. A. y Garza Elizondo, Mario Alberto y De Hoyos R, Dieste y Barboza Quintana, Oralia (2020) Nasal eosinophilic angiocentric fibrosis with IgG4-positive plasma cell infiltration. Malaysian J Pathol, 42 (1). pp. 137-141.

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Resumen

Introduction: Eosinophilic angiocentric fibrosis (EAF) is a rare lesion that predominantly affects the upper respiratory tract. Its etiology is unknown and it has been recently associated with the IgG4- related disease (IgG4-RD) spectrum. To the author’s knowledge, this is the sixth case report of the relationship between EAF and IgG4-RD. Case Report: We report the case of a 37-year-old woman with nasal deformity and facial pain. The lesion was surgically excised. Histological examination revealed features of EAF with an IgG4/IgG plasma cell ratio >73% and 31 IgG4 stained cells per high power field. No clinical or radiological recurrence was detected during follow-up. Serum IgG4 quantification one year after surgery was within normal limits. Discussion: The relationship between both entities may have therapeutic impact because IgG4-RD of the head and neck has a high remission rate with corticosteroids and immunosuppressive therapy. Additional reports of this infrequent disease are necessary to elucidate appropriate treatment and prognosis.

Tipo de elemento: Article
Palabras claves no controlados: Eosinophilic angiocentric fibrosis, IgG4-related disease, IgG4 immunoglobulin, Nasal mass, Rheumatic disease
Materias: R Medicina > R Medicina en General
Divisiones: Medicina
Usuario depositante: Editor Repositorio
Creadores:
CreadorEmailORCID
Sáenz Ibarra, BárbaraNO ESPECIFICADONO ESPECIFICADO
Ceceñas Falcón, Luis ÁngelNO ESPECIFICADONO ESPECIFICADO
Cárdenas de la Garza, J. A.NO ESPECIFICADONO ESPECIFICADO
Garza Elizondo, Mario AlbertoNO ESPECIFICADONO ESPECIFICADO
De Hoyos R, DiesteNO ESPECIFICADONO ESPECIFICADO
Barboza Quintana, OraliaNO ESPECIFICADONO ESPECIFICADO
Fecha del depósito: 16 Mar 2023 15:07
Última modificación: 16 Mar 2023 15:07
URI: http://eprints.uanl.mx/id/eprint/25193

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