Nasal eosinophilic angiocentric fibrosis with IgG4-positive plasma cell infiltration
Sáenz Ibarra, Bárbara y Ceceñas Falcón, Luis Ángel y Cárdenas de la Garza, J. A. y Garza Elizondo, Mario Alberto y De Hoyos R, Dieste y Barboza Quintana, Oralia (2020) Nasal eosinophilic angiocentric fibrosis with IgG4-positive plasma cell infiltration. Malaysian J Pathol, 42 (1). pp. 137-141.
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Resumen
Introduction: Eosinophilic angiocentric fibrosis (EAF) is a rare lesion that predominantly affects the upper respiratory tract. Its etiology is unknown and it has been recently associated with the IgG4- related disease (IgG4-RD) spectrum. To the author’s knowledge, this is the sixth case report of the relationship between EAF and IgG4-RD. Case Report: We report the case of a 37-year-old woman with nasal deformity and facial pain. The lesion was surgically excised. Histological examination revealed features of EAF with an IgG4/IgG plasma cell ratio >73% and 31 IgG4 stained cells per high power field. No clinical or radiological recurrence was detected during follow-up. Serum IgG4 quantification one year after surgery was within normal limits. Discussion: The relationship between both entities may have therapeutic impact because IgG4-RD of the head and neck has a high remission rate with corticosteroids and immunosuppressive therapy. Additional reports of this infrequent disease are necessary to elucidate appropriate treatment and prognosis.
Tipo de elemento: | Article | |||||||||||||||||||||
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Palabras claves no controlados: | Eosinophilic angiocentric fibrosis, IgG4-related disease, IgG4 immunoglobulin, Nasal mass, Rheumatic disease | |||||||||||||||||||||
Materias: | R Medicina > R Medicina en General | |||||||||||||||||||||
Divisiones: | Medicina | |||||||||||||||||||||
Usuario depositante: | Editor Repositorio | |||||||||||||||||||||
Creadores: |
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Fecha del depósito: | 16 Mar 2023 15:07 | |||||||||||||||||||||
Última modificación: | 16 Mar 2023 15:07 | |||||||||||||||||||||
URI: | http://eprints.uanl.mx/id/eprint/25193 |
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