Subchronic Infection of Porphyromonas gingivalis and Tannerella forsythia Stimulates an Immune Response but Not Arthritis in Experimental Murine Model

Hernández Aguas, Jorday y Montiel Hernández, José Luis y De la Garza Ramos, Myriam Angélica y Ruiz Ramos, Rosa Velia y Escamilla García, Erandi y Guzmán García, Mario Alberto y Ayón Haro, Esperanza Raquel y Garza Elizondo, Mario Alberto (2017) Subchronic Infection of Porphyromonas gingivalis and Tannerella forsythia Stimulates an Immune Response but Not Arthritis in Experimental Murine Model. International Journal of Dentistry, 2017. pp. 1-7. ISSN 1687-8728

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Resumen

Studies have proposed that Porphyromonas gingivalis (Pg) and Tannerella forsythia (Tf) promote a nonspecific inflammatory response that could produce systemic disease. Oral inoculation of Pg and Tf on the immune and arthritis response was evaluated in BALB/C mice divided into four groups: (1) sham; (2) food contaminated with Pg/Tf ; (3) complete Freund’s adjuvant (CFA) + Pg/Tf ; and (4) CFA alone. CFA was administered subcutaneously on days 1 and 14. The arthritis response was monitored for 21 days after day 14 of CFA administration. IL-1

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