Acute lymphoblastic leukemia of childhood presenting as aplastic anemia: report of two cases

Villarreal Martínez, Laura y Jaime Pérez, José Carlos y Rodríguez Martínez, Marisol y González Llano, Óscar y Gómez Almaguer, David (2012) Acute lymphoblastic leukemia of childhood presenting as aplastic anemia: report of two cases. Revista Brasileira de Hematologia e Hemoterapia, 34 (2). pp. 165-167. ISSN 1516-8484

[img]
Vista previa
Texto
622.pdf - Versión Publicada
Available under License Creative Commons Attribution Non-commercial No Derivatives.

Download (270kB) | Vista previa

Resumen

Acute lymphoblastic leukemia is the most common malignancy in pediatric patients; its diagnosis is usually easy to establish as malignant lymphoblasts invade the bone marrow and peripheral blood. Some acute lymphoblastic leukemia patients may initially present with pancytopenia and a hypoplastic bone marrow leading to the initial diagnosis of aplastic anemia. In most of these patients clinical improvement occurs, with normalization of the complete blood count within six months, although recovery can also develop a few weeks after initiating steroid therapy. The etiologic relationship between the aplastic anemia features and the subsequent overt development of acute lymphoblastic leukemia has not been established. We describe the cases of two children who presented with severe infection and signs and symptoms of aplastic anemia confirmed by bone marrow aspirate and bone marrow biopsy that developed acute lymphoblastic leukemia thereafter. No specific therapy for aplastic anemia was administered, nevertheless a full spontaneous recovery was observed in both cases. Acute lymphoblastic leukemia was successfully treated with standard chemotherapy, both children remaining in complete remission 16 and 17 months after their initial aplastic anemia diagnosis

Tipo de elemento: Article
Palabras claves no controlados: Acute lymphoblastic leukemia; Aplastic anemia; Pediatrics
Divisiones: Medicina
Usuario depositante: Lic. Josimar Pulido
Creadores:
CreadorEmailORCID
Villarreal Martínez, LauraNO ESPECIFICADONO ESPECIFICADO
Jaime Pérez, José CarlosNO ESPECIFICADONO ESPECIFICADO
Rodríguez Martínez, MarisolNO ESPECIFICADONO ESPECIFICADO
González Llano, ÓscarNO ESPECIFICADONO ESPECIFICADO
Gómez Almaguer, DavidNO ESPECIFICADONO ESPECIFICADO
Fecha del depósito: 24 Mayo 2019 15:01
Última modificación: 20 Ago 2019 19:55
URI: http://eprints.uanl.mx/id/eprint/15024

Actions (login required)

Ver elemento Ver elemento

Downloads

Downloads per month over past year