Neurofilamentopathy in Neurodegenerative Diseases

Liu, Quan y Xie, Fang y Alvarado Diaz, Abdiel y Smith, Mark A. y Moreira, Paula I. y Zhu, Xiongwei y Perry, George (2011) Neurofilamentopathy in Neurodegenerative Diseases. The Open Neurology Journal, 5 (1). pp. 58-62. ISSN 1874205X

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URL o página oficial: http://doi.org/10.2174/1874205X01105010058

Resumen

Neurofilament protein alterations are found in many neurodegenerative diseases, such as amyotrophic lateral sclerosis, Parkinson, Alzheimer, and Charcot-Marie-Tooth. Abnormal modifications of neurofilament, such as mutation, oxidation and phosphorylation, are linked to the disease-related alteration. In this review, the most recent discovery and central arguments about functions, pathological modifications, and genetic mutations related to neurofilaments in neurodegenerative diseases is presented.

Tipo de elemento:

Article

Palabras claves no controlados:

Neurofilament; Alzheimer disease; Parkinson disease; Amyotrophic lateral sclerosis; Phosphorylation; Oxidation; Glycosylation

Materias:

R Medicina > RC Medicina Interna, Psiquiatría, Neurología

Divisiones:

Medicina

Usuario depositante:

Lic. Josimar Pulido

Creadores:

Creador	Email	ORCID
Liu, Quan	NO ESPECIFICADO	NO ESPECIFICADO
Xie, Fang	NO ESPECIFICADO	NO ESPECIFICADO
Alvarado Diaz, Abdiel	NO ESPECIFICADO	NO ESPECIFICADO
Smith, Mark A.	NO ESPECIFICADO	NO ESPECIFICADO
Moreira, Paula I.	NO ESPECIFICADO	NO ESPECIFICADO
Zhu, Xiongwei	NO ESPECIFICADO	NO ESPECIFICADO
Perry, George	NO ESPECIFICADO	NO ESPECIFICADO