Update of the PANCCO clinical practice guidelines for the treatment of ulcerative colitis in the adult population

Juliao Baños, F y Grillo Ardila, C. F. y Alfaro, I. y Andara Ramírez, M. T. y Avelar Escobar, O. y Barahona Garrido, J. y Bautista Martínez, S. y Bosques Padilla, Francisco Javier y De Paula, J. A. y Ernest Suárez, K. y Galiano, M.T. y Iade Vergara, B. y Ibañez, Patricio y Jara Alba, M.L. y Kotze, P. G. y Miranda Ojeda, M. C. y Ortuño Escalante, R. y Otoya- Moreno, G. y Piñol Jiménez, F. N. y Ramos Polo, I. C. y Sambuelli, A. y Toro, M. y Torres, E. A. y Veitia Velásquez, G. R. y Yamamoto Furusho, J. K. y Zaltman, C. y Steinwurz, F. y Vallejo Ortega, M. y Torres Castillo, J. I. y Hamon Pinilla, C. y Calderon Franco, C. H. y Escobar Villegas, A. M. (2022) Update of the PANCCO clinical practice guidelines for the treatment of ulcerative colitis in the adult population. Revista de Gastroenteróloga de México (English Edition), 87 (3). pp. 342-361. ISSN 2255534X

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Resumen

Ulcerative colitis (US) is a chronic disease of unknown etiology. It is incurable and its clinical course is intermittent, characterized by periods of remission and relapse. The prevalence and incidence of the disease has been increasing worldwide. The update presented herein includes the participation of healthcare professionals, decision-makers, and a representative of the patients, all of whom declared their conflicts of interest. Answerable clinical questions were formulated, and the outcomes were graded. The information search was conducted on the Medline/PubMed, Embase, Epistemonikos, and LILACS databases, and covered grey literature sources, as well. The search was updated on November 30, 2020, with no restrictions regarding date or language. The Grading of Recommendations Assessment, Development and Evaluation (GRADE) classification system was implemented to establish the strength of the recommendation and quality of evidence. A formal consensus was developed, based on the RAND/UCLA methodology and the document was peer reviewed. The short version of the clinical practice guidelines for the treatment of ulcerative colitis in the adult population is presented herein, together with the supporting evidence and respective recommendations. In mild-to-moderate UC, budesonide MMX is an option when treatment with 5-ASA fails, and before using systemic steroids. In moderate-to-severe UC, infliximab, adalimumab, vedolizumab, ustekinumab, and tofacitinib can be used as first-line therapy. If there is anti-TNF therapy failure, ustekinumab and tofacitinib provide the best results. In patients with antibiotic-refractory pouchitis, anti-TNFs are the treatment of choice.

Tipo de elemento: Article
Palabras claves no controlados: Ulcerative colitis, Treatment, Inflammatory bowel disease, Mucosal healing, Biologic therapy
Materias: R Medicina > RC Medicina Interna, Psiquiatría, Neurología
Divisiones: Medicina
Usuario depositante: Editor Repositorio
Creadores:
CreadorEmailORCID
Juliao Baños, FNO ESPECIFICADONO ESPECIFICADO
Grillo Ardila, C. F.NO ESPECIFICADONO ESPECIFICADO
Alfaro, I.NO ESPECIFICADONO ESPECIFICADO
Andara Ramírez, M. T.NO ESPECIFICADONO ESPECIFICADO
Avelar Escobar, O.NO ESPECIFICADONO ESPECIFICADO
Barahona Garrido, J.NO ESPECIFICADONO ESPECIFICADO
Bautista Martínez, S.NO ESPECIFICADONO ESPECIFICADO
Bosques Padilla, Francisco JavierNO ESPECIFICADONO ESPECIFICADO
De Paula, J. A.NO ESPECIFICADONO ESPECIFICADO
Ernest Suárez, K.NO ESPECIFICADONO ESPECIFICADO
Galiano, M.T.NO ESPECIFICADONO ESPECIFICADO
Iade Vergara, B.NO ESPECIFICADONO ESPECIFICADO
Ibañez, PatricioNO ESPECIFICADONO ESPECIFICADO
Jara Alba, M.L.NO ESPECIFICADONO ESPECIFICADO
Kotze, P. G.NO ESPECIFICADONO ESPECIFICADO
Miranda Ojeda, M. C.NO ESPECIFICADONO ESPECIFICADO
Ortuño Escalante, R.NO ESPECIFICADONO ESPECIFICADO
Otoya- Moreno, G.NO ESPECIFICADONO ESPECIFICADO
Piñol Jiménez, F. N.NO ESPECIFICADONO ESPECIFICADO
Ramos Polo, I. C.NO ESPECIFICADONO ESPECIFICADO
Sambuelli, A.NO ESPECIFICADONO ESPECIFICADO
Toro, M.NO ESPECIFICADONO ESPECIFICADO
Torres, E. A.NO ESPECIFICADONO ESPECIFICADO
Veitia Velásquez, G. R.NO ESPECIFICADONO ESPECIFICADO
Yamamoto Furusho, J. K.NO ESPECIFICADONO ESPECIFICADO
Zaltman, C.NO ESPECIFICADONO ESPECIFICADO
Steinwurz, F.NO ESPECIFICADONO ESPECIFICADO
Vallejo Ortega, M.NO ESPECIFICADONO ESPECIFICADO
Torres Castillo, J. I.NO ESPECIFICADONO ESPECIFICADO
Hamon Pinilla, C.NO ESPECIFICADONO ESPECIFICADO
Calderon Franco, C. H.NO ESPECIFICADONO ESPECIFICADO
Escobar Villegas, A. M.NO ESPECIFICADONO ESPECIFICADO
Fecha del depósito: 28 Jun 2023 19:20
Última modificación: 04 Mar 2024 15:58
URI: http://eprints.uanl.mx/id/eprint/25651

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