Recent applications of cell-penetrating peptide guidance of nanosystems in breast and prostate cancer (Review)

Longoria García, Samuel y Sánchez Domínguez, Celia Nohemí y Gallardo Blanco, Hugo Leonid (2022) Recent applications of cell-penetrating peptide guidance of nanosystems in breast and prostate cancer (Review). Oncology Letters, 23 (3). p. 103. ISSN 1792-1074, 1792-1082

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Resumen

Cell-penetrating peptides (CPPs) are small peptides from natural sources or designed from other protein sequences that can penetrate cell membranes. This property has been used in biomedicine to add them to biomolecules to improve their capacity for cell internalization and as a guidance tool for specific cell types. CPPs have been shown to enhance cellular uptake in vitro and in vivo, improving the efficacy of anticancer drugs such as doxorubicin and paclitaxel, while also limiting their cytotoxic effects on healthy cells and tissues. The current study reviews the internalization and major therapeutic results achieved from the functionalization of nanosystems with CPPs for guidance into breast and prostate cancer cells in vitro and in vivo. In addition, the practical results obtained are specifi-cally discussed for use as a starting point for scientists looking to begin research in this field.

Tipo de elemento:	Article
Palabras claves no controlados:	Breast cancer, Cell-penetrating peptides, Nanoparticles, Nanosystems, Prostate cancer
Materias:	CONACYT > Biología y Química CONACYT > Ciencias Agropecuarias y Biotecnología CONACYT > Ingeniería y Tecnología CONACYT > Medicina y Ciencias de la Salud
Divisiones:	Medicina
Usuario depositante:	Dr.C. Hugo Gallardo Blanco
Creadores:	Creador Email ORCID Longoria García, Samuel samuel.longoriagr@uanl.edu.mx orcid.org/0000-0002-4056-5343 Sánchez Domínguez, Celia Nohemí celia.sanchezdm@uanl.edu.mx orcid.org/0000-0002-3444-9565 Gallardo Blanco, Hugo Leonid hugo.gallardobl@uanl.edu.mx orcid.org/0000-0002-7816-4967
Fecha del depósito:	24 Sep 2026 15:41
Última modificación:	24 Sep 2026 15:41
URI:	http://eprints.uanl.mx/id/eprint/31450

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