The dawn of the liquid biopsy in the fight against cancer
Domínguez Vigil, Irma Guadalupe y Moreno Martínez, Ana K. y Wang, Julia Y. y Roehrl, Michael H. A. y Barrera Saldaña, Hugo Alberto (2017) The dawn of the liquid biopsy in the fight against cancer. Oncotarget, 9 (2). pp. 2912-2922. ISSN 1949-2553
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Resumen
ABSTRACT Cancer is a molecular disease associated with alterations in the genome, which, thanks to the highly improved sensitivity of mutation detection techniques, can be identified in cell-free DNA (cfDNA) circulating in blood, a method also called liquid biopsy. This is a non-invasive alternative to surgical biopsy and has the potential of revealing the molecular signature of tumors to aid in the individualization of treatments. In this review, we focus on cfDNA analysis, its advantages, and clinical applications employing genomic tools (NGS and dPCR) particularly in the field of oncology, and highlight its valuable contributions to early detection, prognosis, and prediction of treatment response.
Tipo de elemento: | Article | ||||||||||||||||||
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Divisiones: | Medicina | ||||||||||||||||||
Usuario depositante: | Lic. Josimar Pulido | ||||||||||||||||||
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Fecha del depósito: | 01 Mayo 2020 15:56 | ||||||||||||||||||
Última modificación: | 12 Mayo 2020 23:29 | ||||||||||||||||||
URI: | http://eprints.uanl.mx/id/eprint/17421 |
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